91影视破解版

The first example of a direct aromatic nitration reaction in natural product biosynthesis has been reported by the Challis group and collaborators at Cornell University in the leading journal Nature Chemical Biology.

Ada Della Pia and Giovanni Costantini publish the Scanning Tunneling Microscopy entry for the Springer Encyclopedia of Nanotechnology, Bharat Bhushan (ed).

Congratulations to PhD student Becky Wills, selected over more than 100 nominations as a winner of the PG Warwick Award for Teaching Excellence

Professor Rachel O’Reilly wins the 2012 IUPAC-Samsung Young Polymer Scientist Award.

The O’Connor group has developed a computation which simultaneously doubles the resolution, sensitivity and mass accuracy of Fourier Transform Mass Spectrometry at no extra cost.

At a celebration lunch today, the achievements of the Warwick Chemistry Class of 2012 were recognised by the Department. This year's prize winners were:

In their Angewandte Communication P. R. Unwin, J. V. Macpherson, et al. combined high-resolution electrochemical imaging, micro-Raman, and electron-microscopy data to demonstrate that spatially heterogeneous electron-transfer kinetics correlates directly with the local density of electronic states of polycrystalline boron-doped diamond (pBDD). A Multi-Microscopy Approach allowed electrochemical reaction rates to be linked to the corresponding dopant levels in pBDD. See for more details.

Costantini and collaborators report in JACS on dispersions of HBC, an analogue to small graphene flakes.

The Gibson Group in collaboration with Pathologists from the Johannes Guttenburg University (Mainz) have published two studies onto the role of nanoparticle size and coating on their interactions with cells. The aim is to address questions regarding nanoparticle toxicity (if any). Focus was placed on cells from the vasculature (circulation). These cells are often negleted but any injected drug delivery system will encounter several kilometers of these. Several particle formations were found to enter endothelial cells associated with the blood-brain barrier - perhaps the most challenging biological barrier to drug delivery.

This work is published in Biomacromolecules: and Particle Fibre Toxicology:

(Particle Fibre Tox is No 1 Tox. Journal in ISI Citation reports, publishing Primary Research)

Establishing an independent academic career is an exciting and challenging process. The data available for UK chemistry suggests that more women than men find the process not exciting enough or too challenging. A key aspect of success in any career path is finding role models, establishing networks, and being tapped into good sources of information. Our aim is therefore to create opportunities for all of these in the first (and subsequent) Irène Joliot-Curie conference.

Prof. Greg Challis and Dr Lijiang Song, in collaboration with researchers at the University of Paris, report in Angewandte Chemie a hitherto unanticipated pathway for the biosynthesis of pyrroles from sugars. Using a combination of genetic engineering, isolation, structure elucidation, synthesis and feeding of biosynthetic intermediates, and incorporation of stable isotope-labelled precursors, the researchers showed that a carbohydrate, most likely N-acetylglucosamine-1-phosphate, is elaborated to the 4-acetamidopyrrole-2-carboxylate building blocks of the DNA-binding antibiotic congocidine (also known as netropsin). The assembly of pyrroles from carbohydrates is unprecedented in Nature and raises several intriguing questions regarding the mechanisms of the reactions involved. See for further details.